The effect of insulin resistance on cognitive impairment in elderly patients with metabolic syndrome
HAN Rui
LI Yun
QIAN Yuying
WANG Jieyu
ZHANG Yaxin
MA Lina
Abstract：Objective To explore the effect of insulin resistance on cognitive impairment in elderly patients with metabolic syndrome. Methods One hundred and thirty-five elderly patients with metabolic syndrome were divided into two groups: cognitive impairment group (case group,n=60) and non-cognitive impairment group (control group,n=75), gender, age, cultural level, BMI, SBP, DBP, TG, LDL-C, SCr, FPG and HOMA-IR were compared between the two groups, and logistic regression was analyzed.Results Compared to the control group, the cultural level of cognitive impairment group was lower, the level of BMI was higher, and the HOMA-IR were higher (P<0.01). In the logistic regression cultural level and HOMA-IR were independent factors.Conclusion The cultural level and HOMA-IR were independent factors of cognitive. Insulin resistance has an effect on the cognitive impairment in elderly patients with metabolic syndrome.
Keywords：Metabolic syndromeInsulin resistanceCognitive impairmentElderly
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 473-476 )