Clinical research for the treatment of given immune enteral nutrition by the jejunum nutrition tube on the patients with severe acute pancreatitis
LIU Bo
WANG Yumei
HUO Shuang
ZHOU Shaoying
XU Shuai
WANG Xiaoli
YAN Tingqi
Abstract：Objective To investigate the effect of enteral nutrition support in the treatment of severe acute pancreati -tis with nutritional index , immune index and inflammatory response index .Methods We collected 72 patients with severe a-cute pancreatitis from January 2013 to December 2015 .They were randomly divided into research group and control group , each group had 36 cases.All patients were treated with conventional treatment , research group were received immune enteral nutrition therapy by jejunum nutrition tube , control group were received parenteral nutrition support .Compare two groups after treatment, patients’ nutrition indicators (Alb, PAB), humoral immunity (IgA, IgG, IgM), cellular immunity (TLC, CD3 +, CD4 +) and inflammatory indicators (CRP, TNF-α, IL-6) changes.Results Two groups of patients given different nutrition after treatment , the indicators were obviously improved .At 7 days and 14 days, the ALB and PAB levels of the re-search group were significantly higher than that of the control group ( t 7 =1.717, t 7 =2.957;t 14 =2.411, t 14 =2.182, P <0.05);Treatment for 14 days, the IgA, IgG, IgM, TLC, CD3 +, CD4 +of the research group were improved significantly better than the control group ( t =2.031, t =2.106, t =2.198, t =2.050, t =2.182, t =1.850, P <0.05).At the same time, the CRP, TNF-α, IL-6 of the research group declined significantly than the control group ( t =2.437, t =1.705, t =2.697, P <0.05).Conclusion The jejunum nutrition tube given immune enteral nutrition in treatment of severe acute pan -creatitis can effectively improve the nutritional status and immune function of patients , reduce the inflammatory reaction in pa-tients with acute reaction period , so as to improve the prognosis and improve the clinical efficacy .
Keywords：Immune enteral nutritionSevere acute pancreatitisNutrition indicatorsImmunologic functionInflam-matory indicators
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 80-83,86 )