Perioperative evaluation of cardiac function of lung cancer patients by SPECT

ZHAO Zheng; YANG Xiaoguang; SU Chunyong; MA Xiaogang; NIE Xiaojin; REN Libing

doi:10.3969/j.issn.1671-6450.2017.01.011

Abstract：Objective To investigate the clinical value of single photon emission computed tomography ( SPECT ) myocardial perfusion imaging in the evaluation of cardiac function in patients with lung cancer during perioperative period . Methods From January 2013 to January 2016 , in the Department of thoracic surgery of Handan Central Hospital , surgical treatment of 63 cases of patients with lung cancer , including lobectomy 42 cases, 21 cases of lung resection were enrolled , be-fore and after surgery around 10 d, SPECT myocardial perfusion imaging and echocardiography were performed , compared be-fore and after the operation of different examination methods of left ventricular ejection fraction ( LVEF) , end diastolic volume ( LVEDV) , end systolic volume ( LVESV) and other indicators ’ differences .Results Fifty myocardial perfusion images were normal (79.37%) before surgery, 34 myocardial perfusion images were normal (53.97%) post-operative (χ2 =9.143, P =0.002);After surgery, left ventricular ejection fraction (LVEF) compared with before surgery was significantly reduced (t =3.248, P =0.002;t =4.178, P =0.000), the difference between the two groups were statistically significant ( t =2.247, P =0.028);SPECT myocardial perfusion imaging and echocardiography left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), left ventricular ejection fraction (LVEF) were not statistically significant different ( P >0.05).Conclusion SPECT myocardial perfusion imaging to assess cardiac function in perioperative patients with lung cancer is more accurate and objective , and it is worth to be popularized in clinical application .