The relationship between positive fluid balance and prognosis in the septic patients
WU Ying
HEI Zaiming
DANG Zongyan
ZHANG Wei
Abstract：Objective The aim of this study was to analyze whether a positive fluid balance and its persistence over time was a prognostic factor in septic patients .Methods From January 2015 to December 2015 in Shanghai City , Putuo Dis-trict Liqun Hospital emergency medicine EICU treated 92 sepsis patients met the inclusion criteria , based on the 28 day sur-vival, they were divided into death group (34 cases) and survival group (58 cases), respectively.Statistical analysis of 2 groups of patients during treatment for 5 consecutive days , daily fluid intake and output volume and balance the cumulative to-tal amount of liquid , analysis of the relationship between fluid balance and the prognosis of patients .Result Of the 92 pa-tients, 34 died (38.0%).Mean daily fluid intake was higher in non-survivors than in survivors( t 1d =0.191, P 1d =0.849;t2d =-0.327, P 2d =0.745;t 3d =-4.490, P 3d=0.000;t 4d=-3.468, P 4d =0.001;t 5d=-2.820, P 5d =0.006), but output volumes were similar( t 1d=1.414, P 1d=0.161;t 2d =0.694, P 2d =0.490;t 3d=3.617, P 3d =0.010;t 4d =6.282, P 4d =0.000;t 5d =6.819, P 5d =0.000).The daily fluid balance ( t 1d =-0.857, P 1d =0.394;t 2d =-0.893, P 2d =0.337;t 3d =-7.841, P 3d =0.000;t 4d =-12.023, P 4d =0.000;t 5d=-10.195, P 5d =0.000 ) and the cumulative amount of liquid( t 1d =-0.857, P 1d=0.394;t 1+2d =-1.275, P 1+2d =0.206;t 1+2+3d =-3.735, P 1+2+3d=0.000;t1+2+3+4d =-6.545, P 1+2+3+4d =0.000;t 1+2+3+4+5d =-9.384, P 1+2+3+4+5d=0.000) were more in the non-survivors.It has statistical significance .The negative fluid balance of the fourth day had good prognosis in patients with sepsis (χ22d =0.359, P 2 =0.549,χ23d =9.816, P 3 =0.020,χ24d=54.314, P 4 =0.000,χ25d =38.875, P 5 =0.000).Conclusion In septic patients , the persistence of a positive daily fluid balance over time was quite strongly associated with a higher mortality rate.
Keywords：SepticopyemiaIntake and output volume balanceLiquidElementDeath
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1284-1288 )