Clinical effect of minimally invasive surgical treatment of cerebral hemorrhage by minimally invasive catheter suction and drainage influence on nerve function and inflammatory cytokines levels
YANG Yongqing
YANG Ruilin
ZHAO Zhijing
DIWU Feihu
Abstract：Objective To observe the effect of minimally invasive surgery on the patients with cerebral hemorrhage and the effect on the nerve function and the level of inflammatory cytokines in patients with cerebral hemorrhage .Methods Ninety-two cases of patients with intracerebral hemorrhage were selected , which were treated in hospital from January 2015 to January 2016, and they were divided into the study group (46 cases) and control group (46 cases).The patients of control group were treated with conservative treatment , including mannitol , albumin or furosemide and other dehydration drugs for re-ducing the intracranial pressure , maintain water balance solution , and close monitoring of vital signs of patients .On the basis of the conventional treatment , the patients of study group were treated with minimally invasive drilling catheter hematoma aspi -ration liquefied drainage operation .Compare the clinical efficacy , the incidence of re-bleeding, mortality rate, complications, and changes of neurological function deficit scores ,serum hs-CRP, TNF-α, IL-6 of two groups.Results The patients of the study group got a total efficiency of 91.3%, which was significantly better than the 71.7%of the control group (χ2 =5.845, P =0.016);The neurological function deficit scores ( t =12.629、11.381, P =0.000、0.000),hs-CRP, TNF-α, IL-6, and mortality rate of the study group were significantly less than those of the control group after the treatment (χ2 =6.685,χ2 =4.865,χ2 =7.967, all P <0.01);The incidence of re-bleeding of the study group were significantly higher than those of the control group after the treatment (χ2 =13.904, P =0.000);There were urinary tract infection , lung infection, gastrointesti-nal bleeding , venous thrombosis and other complications occurred in patients of all two groups during treatment , but there was no significant difference between the two groups (χ2 =0.199,χ2 =0.751,χ2 =0.474,χ2 =2.224, all P >0.05).Conclu-sion It demonstrated that treating patients with intracerebral hemorrhage , minimally invasive catheter pumping liquefied drainage operation can get exact clinical efficacy , effectively improve the neurological function , reduce the inflammatory reac-tion, which is help to improve the prognosis of patients , and worthy of clinical application .
Keywords：Intracerebral hemorrhageMinimally invasive catheter pumping liquefied drainage operationNeurologi-cal functionInflammatory cytokines
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 912-915 )