Bronchoscopy APC combined with CO2 cryotherapy treatment and its effect on the airways, blood gas analysis, pul-monary function of tuberculous airway stenosis
XU Chunyan
QIU Zhongmin
LV Hanjing
YANG Zhongming
Abstract：Objective To observe the effect of bronchoscope argon plasma coagulation resection ( APC) combined with CO2 cryotherapy in treatment of tuberculous airway stenosis and its impact on the clinical effect of the airway, blood gas a-nalysis, pulmonary function.Methods Select from 2014 June to 2015 June, 144 cases of tuberculous airway stenosis in Shanghai Tongji Hospital as the research group, they were randomly divided into observation group and control group with 72 cases in each group.2 groups of patients were given conventional inhalation, anti-TB drugs, local injection therapy, the con-trol group were received bronchoscopy APC treatment, the observation group also combined CO2 cryotherapy, once a week.2 groups of patients were treatment for 6 months.2 groups of patients before and after treatment, airway diameter, shortness of breath level, KPS score, changes PaCO2 , PaO2 , SpO2 and FEV1/FVC and adverse reactions were recorded.Results Obser-vation group’s total effective rate was 91.7%, which was significantly higher than the 75.0%of control group ( P <0.05);compared with before treatment, after treatment, the two groups of patients’ airway diameter, KPS score, PaO2 , SpO2 , FEV1/FVC significantly increased, shortness of breath grade, PaCO2 significantly decreased ( P <0.05) , wherein the degree of improvement in the observation group were better than the control group ( P <0.05);2 group patients’ active bleeding, fever, oxygen desaturation, mild cough and other adverse symptoms were returned to normal after symptomatic treatment;he-modynamic abnormalities did not occur and other serious adverse reactions were not found.Conclusion Bronchoscopy APC combined with CO2 cryotherapy in treatment of tuberculous airway narrowing’ s effect is obvious and safe, it is advantageous to improve the level of lung function and the quality of life of patients, should be widely applied.
Keywords：Major airway stenosistuberculosisBronchoscopyCryotherapyPulmonary function
Publication Date：2016-01-01