Efficacy of noninvasive positive pressure ventilation on patients with chronic obstructive pulmonary disease complicat-ed with pulmonary heart disease in acute exacerbation period and the effect on blood gas and inflammatory index
LEI Yingjun
HU Zhenhong
LIU Haichao
Abstract：Objective To observe the effect of noninvasive positive pressure ventilation on patients with chronic ob-structive pulmonary disease( COPD) complicated with pulmonary heart disease in acute exacerbation period and the effect on blood gas and inflammatory index.Methods Selected 80 cases of COPD combined with pulmonary heart disease acute exacer-bation patients from 2013 March to 2015 March treated at Guangzhou Military Region, Wuhan General Hospital, according to the random number table method, these patients were divided into observation group and control group with 40 cases in each group.The control group was treated with routine treatment for COPD combined with pulmonary heart disease, and the obser-vation group was treated with noninvasive positive pressure ventilation on the basis of conventional treatment.After treatment, the therapeutic effect of the two groups were compared, detected and recorded all patients'before and after treatment blood gas index [ arterial carbon dioxide partial pressure value ( PaCO2 ) , the arterial oxygen partial pressure ( PaO2 ) , oxygen satu-ration (SaO2, pH)] and inflammatory factor (CRP and BNP) level changes.Results After treatment,the observation group's total efficiency was 95.0%,which was higher than control group's 77.5%(χ2 =5.165, P <0.05);compared with before treatment, blood gas index,CRP and BNP levels were improvement after treatment, and the observation group better than the control group ( P <0.05).Conclusion Non invasive positive pressure ventilation in the treatment of chronic ob-structive pulmonary disease with acute exacerbation of pulmonary heart disease patients showed good clinical effect, it can ef-fectively improve the patient's blood gas indicators, it is worth promoting the application.
Keywords：Noninvasive positive pressure ventilationChronic obstructive pulmonary diseaseAcute exacerbation of pulmonary heart diseaseBlood gas analysisInflammatory factors
Publication Date：2016-01-01
Pages：4( 233-235,240 )