Changes and significance of red cell distribution width in patients with chronic obstructive pulmonary disease at differentlevels
PENG Yalan
LIU Jianhong
WANG Haixia
SHEN Chunying
LV Lin.
Abstract：Objective To explore the changes of red cell distribution width ( RDW) in patients with chronic obstruc-tive pulmonary disease ( COPD) at different levels and its significance.Methods From January 2013 to January 2015, 80 patients with COPD in Panzhihua City, Sichuan Province were divided into group A (grade 0), group B (gradeⅠ), group C ( gradeⅡ) and group D ( gradeⅢ) .Compared the four groups of patients'RDW, hemoglobin ( Hb) , red blood cell count ( RBC) , white blood cell count ( WBC) , brain natriuretic peptide ( BNP) , C-reactive protein ( CRP) and carbon dioxide into pressure ( PaCO2 ) oxygen partial pressure ( PaO2 ) , and factors related to the gradeⅢpatients with chronic obstructive pul-monary disease (COPD).Results The 4 groups had no statistically significant difference of Hb and RBC ( P >0.05). RDW, WBC, BNP, CRP and PaCO2 in the order of group D >group C >group B>group A, Level of PaO2 in the order of group A >group B >group C >group D, the difference has statistical significance ( P <0.05).ClassⅢchronic obstruc-tive pulmonary disease ( COPD) patients'RDW and oxygen points pressure was negative correlated ( r =-0.395, P <0.01), and BNP and CRP were positively correlated ( r =0.783, r =0.362, P <0.05).Conclusion It proved that the COPD patient's RDW and PaO2 showed negative correlation, and can better reflect the patient's inflammatory reaction level, it can be used as severity index for patients with COPD.
Keywords：Chronic obstructive pulmonary diseaseRespiratory failureRed cell distribution widthInflammatory re-sponse
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 229-232 )