The impacts of CRP, PCT, WBC and cellular immune parameters of Tanreqing injection in patients with severe pneumonia

YUAN Rongzheng; WANG Hui; HAN Wenhui; MA Mingchao; YANG Xiaoli

doi:10.3969/j.issn.1671-6450.2016.02.010

Abstract：Objective To discuss the effect of Tanreqing injection on patients with severe pneumonia C reactive pro-tein ( CRP) , procalcitonin ( PCT) ,WBC and the index of cellular immunity.Methods Select 120 cases of severe pneumonia patients from June 2012 to June 2015 at Qingdao Jiaozhou Central Hospital, they were divided into observation group and con-trol group, 60 cases in each group, according to the random number table method, while the control group was given conven-tional therapy, the observation group based on the control group’ s treatment, also added Tanreqing injection, compared the two groups’ clinical therapeutic effect and CRP, PCT and the index of cellular immunity.Results In observation group, the total efficiency was 96.7%.In control group, the total effective rate was 80.0%, the difference was statistically significant (χ2 =8.063, P <0.05).Compared with before treatment, after treatment, the two groups’ CRP, PCT and WBC levels sig-nificantly reduced ( P <0.05), and observation group’s after the treatment CRP, PCT and WBC levels were significantly lower than those of the control group ( P <0.05) .The ratio of CD4 +Th17 cell ratio, Th17 /Treg and CD4 +CD25 +Treg cells in the two groups after treatment were significantly improved than before treatment, after treatment, the observation group’s CD4 +Th17 cell rate lower than control group, the ratio of Th17 /Treg and CD4 +CD25 +Treg cells were higher than control group ( P <0.05).Conclusion The Tanreqing injection can effectively reduce patients’ severe pneumonia serum CRP,PCT and WBC levels, improve the therapeutic effect.