The correlation of extravascular lung water index with plasma doluble triggering receptor expressed on myeloid cell 1 in patients with severe pneumonia
TAO Fei
WU Xiang
HU Guifang
DENG Liehua
YAO Huaguo
Abstract：Objective To investigate the relationship between the serum levels of EVPWI in patients with severe pneumonia and the plasma soluble triggering receptor-1 (sTREM-1).Methods A total of 32 cases of patients with severe pneu-monia from February 2012 to May 2015 at Guangdong Medical College Affiliated Hospital were enrolled, they were divided ac-cording to 28 day prognosis into survival group ( n =23) and death group ( n =9), dynamic monitoring patients in ICU 1, 3, 5 day’s EVLWI and pulmonary microvascular permeability determination (PVPI) and changes of plasma sTREM-1 level. Analysis EVLWI and PVPI and plasma sTREM-1 level’ s correlation.Results Patients with severe pneumonia, death and survival group had no significant difference ( P >0 05) of first day ICU admission’ s EVLWI, PVPI, sTREM-1 level; the survival group’s plasma EVLWI, PVPI, sTREM-1 level in the first and third, fifth days gradually decreased ( P <0.05), whereas no significant fluctuations in the death group ( P >0.05); at third, fifth days, death group’ s EVLWI, sTREM-1 levels were significantly higher than the survival group ( P <0.05), the fifth day’s PVPI was significantly higher than surviv-al group ( P <0 05.); EVLWI, PVPI and sTREM-1 levels were significantly correlated ( r =0.457, r =0.412, P <0.05).Conclusion PVPI, EVLWI can indirectly reflect the level of inflammatory factors in patients with severe pneumonia, help to assess the condition of patients with severe pneumonia.
Keywords：Severe pneumoniaExtravascular lung water indexSoluble triggering receptor expressed on myeloid ceils-1
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 143-146 )