The influence of fast track surgery on nutritional index and immune function in pancreatic cancer patients
MENG Haichao?
GAO Xiaobin
WANG Likun
WU Xueliang
LIU Lijie
WANG Zhengtian
MA Qiuyun
Abstract：Objective To investigate the effect of rapid rehabilitation surgery ( FTS ) on nutritional status and im-mune function of patients with pancreatic cancer after surgical operation. Methods Selected 120 cases of patients with pan-creatic cancer surgery, they were randomly divided into fast track surgery group ( observation group, 60 cases) and conven-tional treatment group ( control group, 60 cases) , the control group using the traditional methods of health care, the observa-tion group using fast track surgery nursing, each period’s hemoglobin (Hb), serum albumin (Alb), prealbumin (PAB), turn iron albumin ( TRF) and other nutritional indicators and IgA, IgG, IgM, CD3+,CD4+, CD4+ /CD8+ immune index concen-tration were tested, and analysis were performed. Results 2 groups of patients’ preoperative Hb, Alb, PAB, TRF concentra-tion had no significant differences ( P >0. 05);the first day after operation, these indices were significantly decreased ( P <0. 05), the fifth day after operation, the observation group’s serum PAB, TRF concentration was significantly higher than that of control group ( P <0. 05). IgA, IgG and IgM concentrations at postoperative day 1 were significantly decreased than the preoperative in both of the two groups ( P <0. 05), but the control group decreased more significantly, after operation’s 5th day, observation group recovered to preoperative levels, but control group remained significantly lower than preoperative level ( P <0. 05). CD3+, CD4+, CD4+ /CD8+ concentration on postoperative day 1 was significantly decreased in both of the two groups ( P <0. 05), but the control group decreased more significantly, after operation’s 5th day, observation group recov-ered to preoperative levels, but control group remained significantly lower than preoperative levels ( P <0. 05). Conclusion Rapid rehabilitation surgery can significantly improve the nutritional status of pancreatic cancer patients after surgery, pro-tect the immune function, accelerate postoperative recovery, it is worthy of application.
Keywords：Rapid rehabilitation surgeryPancreatic cancerNutritional statusImmune function
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 838-841 )