Reversible splenial lesion syndrome in 5 patients
JIAO Lidong
WANG Xianling
YANG Yanhui
WANG Xiangbo
Abstract：Objective To investigate the clinical features and MR features of the reversible corpus callosum lesion syndrome. Methods From January 2013 to December 2014, retrospective analysis the clinical and imaging data of 5 cases of the reversibility of the corpus callosum splenium lesion syndrome from Capital Medical University Xuanwu Hospital, Depart-ment of Neurology. Results In the 5 patients, male of 3 cases, female of 2 cases. Fever occurred in 4 cases, diarrhea in 2 cases, abnormal mental behavior in 4 cases, and epilepsy in 2 cases. All 5 cases underwent lumbar puncture expect 1 patient, CSF WBC 1 340 × 106/L, the remaining 4 cases were normal routine and biochemical CSF. 5 patients were underwent head MR 3-11 days after the onset, all were displayed as the corpus callosum pressure abnormal signal, T1WI showed low or slightly low signal, T2WI showed high or slightly high signal. DWI was high signal, and the enhanced scan revealed no en-hancement. 3 patients were treated with acyclovir treatment, 1 cases were treated with Ceftriaxone and mannitol, 1 cases trea-ted with methylprednisolone. The symptoms disappeared from 11 to 26 d after the onset of the disease, and the clinical symp-toms were completely relieved after 20 to 33 days. Conclusion Reversible corpus callosum body pressure lesion syndrome can be found in a variety of diseases, with mild clinical symptoms, radiographic changes reversible, the prognosis is good.
Keywords：Reversible splenial lesion syndromeEncephalitisMagnetic resonance imagingDiagnosisTreatment
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 800-802 )