The study of vulnerable plaque in coronary artery using intravascular ultrasound virtual histology
ZHAO Wei
WANG Tian
CUI Lianqun
CAO Wancai
LI Tingting
XU Hong
LI Ying
Abstract：Objective To analyze the characteristics of stable angina pectoris ( SAP) and acute coronary syndrome ( ACS) coronary plaque composition using intravascular ultrasound virtual histology ( IVUS-VH) .Methods From February 2014 to January 2015, 120 cases of patients with coronary heart disease were enrolled, including 60 cases of patients with SAP, 60 cases of patients with ACS, after the completion of coronary angiography ( CAG) , the culprit lesion were detected by intravascular ultrasound ( IVUS) , save ordinary gray scale image and virtual histology ultrasound data and plaques characteris-tics were analyzed using virtual histology.Results The ACS group plaque detection rate was significantly higher than that of SAP group (81.7%vs.30.0%, P <0.01).ACS group’s ordinary gray scale ultrasound plaque eccentricity index (EI) and vascular remodeling index (RI) were greater than SAP group ( t =-2.985, t =-3.047, P <0.01), most culprit lesion of ACS group were eccentric plaques, vascular remodeling was mainly positive remodeling.In plaque composition, ACS group mainly were fiber lipid composition ( yellow) and necrotic elements ( marked in red) , and SAP group were fiber components ( green) and calcified components ( white label) .Conclusion IVUS-VH in detection of unstable plaque has a very high spe-cificity and sensitivity, using IVUS-VH to analyze lesions may change the current status of the treatment of percutaneous coro-nary intervention.
Keywords：Vulnerable plaqueCoronary arteryIntravascular ultrasound virtual histology
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 668-671 )