The diagnostic value of h igh frequency ultrasound and contrast enhanced ultrasound in wrist joints aerly damage of rheumatoid arthritis and comp arison with MR
XU Caina
IL Li
WANG Xiaoyan
LI Xuming
ZHENG Guimin
Abstract：Objective To investigate the early diagnostic value of high frequency ultrasound ( HFUS) and contrast-enhanced ultrasound ( CEUS) in patients with rheumatoid arthritis ( RA) and compared with MR imaging.Methods Ninety-six patients with rheumatoid arthritis with a total of 192 joint were received HFUS, CEUS exam, the results were compared withMRI.Results (1)HFUSexamination,RApatients’jointeffusion,synovitis,tenosynovitis,destructionofcartilage and bone erosion display rates were 83.33% (160/192) and 73.96% (142/192), 60.42%(116/192), 77.08%(148/192).CEUS’s display rates was 85.93% (165/192), 84.37% (162/192), 67.71% (130/162) and 73.43% (141/192) respectively;MR detection rate were 82.29%(158/192), 74.48%(143/192), 71.35%(137/192), 100%(192/192) respectively.HFUS measured synovial thickness was (3.07 ±1.55 mm), after contrast,CEUS measured the synovial thickness was (3.83 ±1.72) mm, compared with the conventional ultrasonic measurement, value was increased and after contrast enhancement, synovium showed homogeneous enhancement, internal microcirculation displayed more clearly.( 2 ) RA patients’ HFUS and CEUS examination compared with MR showed that ultrasound of joint effusion and synovial lesions de-tection rate are basically the same as MR ( P >0.05); ultrasonic for detection of tenosynovitis and cartilage, bone erosion were lower than MR (χ2 =4.63,χ2 =4.44,χ2 =4.44,χ2 =14.22, P <0.05).Conclusion Ultrasound for joint effusion and synovial lesions detection were consistent with MR examination HFUS and CEUS can provide the basis for diagnosis of ear-ly RA.
Keywords：Rheumatoid arthritisSynovitisHigh frequency ultrasoundContrast-enhanced ultrasoundMagnetic res-onance imagingDiagnosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 600-603 )