Clinical effect of Shensongyangxin capsule and metoprolol in elderly patients with arrhythmia
HOU Mingqiao
ZHANG Chunyuan
QIU Ling
Abstract：Objective To observe the therapeutic effect of Shensongyangxin capsule combined with metoprolol in the treatment of elderly patients with coronary heart disease and arrhythmia, as well the effect on blood lipid and blood pressure, the level of BNP.Methods From 2013 August to 2014 October, 132 cases of elderly patients with coronary heart disease and arrhythmia were randomly divided into observation group and control group, each group with 66 cases.2 groups of patients were given routine drug treatment, the control group was given metoprolol tartrate tablets tid, the initial dose was 25 mg, ad-justed the dosage according to the blood pressure levels and heart rate;in observation group, based on the theraphy as in the control group, also added with Shensongyangxin capsule, 1.2 g, tid.4 weeks as 1 course.Before and after treatment’ s the clinical curative effect and blood pressure (systolic blood pressure (SBP), diastolic blood pressure (DBP), blood lipid [tri glycerin (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol ( HDL-C) , brain natriuretic peptide ( BNP) ] changes were compared between the 2 groups of patients.Results After the treatment, the total effective rate of observation group was 89.4%, which was higher than that of the control group’s 71.2%(χ2 =10.469, P <0.05).After the treatment, ventricular contraction, atrial premature contraction, junctional contractions, paroxysmal atrial fibrillation significantly reduced ( P <0.05), and the observation group was significantly better than the control group ( P <0.05) ;after treatment, SBP, TC, TG, DBP, LDC-C and BNP level decreased significantly in both of the two groups, HDL-C increased significantly, and the observation group’ s blood pressure, blood lipids and the level of BNP was better than the control group ( P <0.05).Conclusion It proved that combining the Shensongyangxin capsule and meto-prolol in treatment of elderly patients with coronary heart disease combined with arrhythmia could effectively improve the level of blood lipid and blood pressure, BNP, it is worthy of clinical application.
Keywords：Coronary artery diseaseArrhythmiaShensongyangxin capsuleMetoprolol
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 508-510,515 )