The clinical efficacy of deep brain stimulation of the lateral dorsal subthalamic nucleus for patients with Parkinson's disease
CHEN Baoyou
LI Qiang
LIU Aibin
Abstract：Objective To observe the effect and safety of subthalamic nucleus lateral dorsal electrical stimulation for the treatment of Parkinson 's disease .Methods Subthalamic nucleus lateral dorsal electrical stimulation was performed in 15 patients with Parkinson 's disease, and according to the efficacy and safety of treatment , the efficacy and adverse reactions of treatment were analyzed and evaluated .Results Compared with before surgery , after treatment, patients'UPDRS III score and UPDRS II score were significantly improved ( P <0.05, P <0.01);dosage, onset time, duration of efficacy were improved ( P <0.05);Schwab, Hoehn-yahr scores showed that compared with preoperative , postoperative patients has improved sig-nificantly in the "on"and "off"period ( P <0.05, P <0.01);compared with the preoperative , motor function scores were improve postoperatively ( P <0.05, P <0.01);after treatment, related adverse reactions , such as open eye difficulties were occurred, but through the adjustment of stimulation , these parameters were improved .Conclusion The subthalamic nucleus lateral dorsal electrical stimulation treatment method has a good therapeutic effect and safety for treating of Parkinson 's disease.
Keywords：Subthalamic nucleusParkinson's diseaseElectric stimulationClinical effect
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 23-25 )