Comparative study of different hemodialysis for micro inflammatory state in chronic renal failure
LIU Yan
CHENG Jianzhao
GUO Ziyan
Abstract：Objective To compare the effects of conventional hemodialysis (HD),high flux hemodialysis(HFHD) and hemoperfusion ( HP) on micro inflammatory state in patients with chronic renal failure .Methods From 2010 June to 2013 August, 45 patients with chronic renal failure received hemodialysis treatment were enrolled , a retrospective analysis of HD , HFHD,HP in 3 different ways for hemodialysis patients before treatment , after the first time treatment and 3 months after treat-ment’s advanced glycation end products (AGEs), C reactive protein (CRP), interleukin 6 (IL-6), tumor necrosis factor al-pha (TNF alpha) levels’ change.Results Compared with those before treatment , after 3 months of treatment, patients in the HP group’s CRP, AGEs, IL-6, TNF-alpha level and HFHD group’s AGEs, IL-6, TNF-alpha level were significantly de-creased with statistical significance ( P <0.05);3 groups of patients after 3 months of treatment, the level of AGEs, CRP af-ter 3 months of treatment , the level of IL-6, TNF-alpha after the first time treatment and 3 month of treatment were significant-ly changed ( P <0.05), HP group and HFHD group was superior to group HD , and HP group was better than HFHD group ( P <0.05).Conclusion Hemoperfusion could reduce AGEs ,CRP, IL-6, TNF-alpha level in the blood in patients with chronic renal failure to improve the micro inflammatory state ,compared with conventional hemodialysis and high-flux hemodia-lysis, it had certain advantages , would be a better choice in the clinical practice .
Keywords：Renal failurechronicHemodialysisHigh flux hemodialysisHemoperfusionMicro inflammatory stat
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1251-1253 )