Effect of early enteral nutrition support on nutritional status, immune function and prognosis for patients with severe stroke
YU Xiaoling
ZHOU Shijun
PENG Haifeng
YANG Xubo
TANG Haiyang
Abstract：Ob jective To analyze the early applications of immune enteral nutrition support treatment effect on nutri -tional status, immune function and prognosis of patients with severe stroke .Methods Sixty-six cases of severe stroke patients were randomly divided into 2 groups by digital table method , 33 cases in each group .On the basis of conventional therapy , the control group was given common liquid diet feeding;the observation group was given enteral nutrition support treatment , im-mune function , nutritional condition and prognosis of the patients in the 2 groups after 15 d treatment were compared .Results On the fifteenth days of treatment, nutrition indicators revealed: serum total protein (TP), albumin (Alb), prealbumin (PA), hemoglobin (Hb) in control group were (61.42 ±3.34) g/L,(34.04 ±3.92) g/L,(226.3 ±17.5) mg/L,(111.7 ± 12.8) g/L, the observation group were (67.16 ±4.41) g/L,(37.46 ±3.25) g/L,(278.6 ±16.1) mg/L, (127.4 ±13.3) g/L;immune function index:control group’s IgG, IgM, IgA, CD4, CD8, CD4/CD8 were (13.04 ±1.24) g/L, (1.78 ± 0.43) g/L, (2.37 ±0.76) /L,(36.92 ±1.94)%, (25.79 ±1.88)%, (1.27 ±0.12);observation group were (16.49 ± 1.16) g/L, (2.32 ±0.31) g/L, (2.84 ±0.53) g/L, (41.16 ±2.01)%, (27.84 ±1.93)%, (1.56 ±0.19), the index of both groups were decreased, but in control group decreased significantly than those in the observation group (P <0.05). Complications:control group patients ’ pulmonary infection, heart failure, renal failure, pressure ulcers, urinary tract infec-tion, stress ulcer occurred rate were 24.2%, 18.2%, 21.2%, 15.2%, 18.2%, 36.4%, respectively, in the observation group were 12.1%, 9.1%, 9.1%, 6.1%, 6.1%, 24.2%, which were lower than that of control group , but no significant difference was observed between two groups ( P >0.05).Conclusion The application of early enteral nutrition support can improve the prognosis of patients with severe stroke , effective correct the hypoproteinemia , improve immunity, and reduce the complication.
Keywords：Cerebral strokeEnteral nutritionNutritional statusImmune functionPrognosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1114-1117 )