The effect of human urinary kallidinogenase on patients with cerebral infarction and expressions of hs-CRP and PCT
HUANG Rong
WANG Chong
WU Jiayong
Abstract：Objcet ive To investigate the effect of human urinary kallidinogenase on treatment in patients with cere -bral infarction and expression of serum high sensitivity C reactive protein (hs-CRP) and procalcitonin (PCT).Methods 140 cases of patients with cerebral infarction were enrolled , they were randomly divided into 2 groups, 70 cases in each group.The control group was given conventional treatment ( ginkgo leaf extract and dipyridamole +clopidogrel +aspirin) , the observa-tion group besides the conventional treatment , combined with human urinary kallidinogenase , a total of 14 d treatment were completed.Before treatment and after treatment , the expression of hs-CRP and PCT of patients with cerebral infarction were detected, cerebral volume were measured, and compared the United States National Institutes of Health Stroke Scale (NIHSS) score.Results After 14 d’s treatment, 2 groups of cerebral infarction volume were decreased ( P <0.05), NIHSS score were decreased ( P <0.05), and the observation group’s infarct volume decrease and NIHSS score were better than that of control group ( P <0.05).After treatment, the 2 groups’ hs-CRP and PCT were decreased ( P<0.05), and the observa-tion group decreased significantly than that in the control group ( P <0.05).Conclusion The effect of human urinary kal-lidinogenase on patients with cerebral infarction is good , and can effectively reduce the expression of hs-CRP and PCT, it is worthy be applied in clinical treatment .
Keywords：Human urinary kallidinogenaseCerebral infarctionHigh sensitivity C reactive proteinProcalcitonin
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1108-1110 )