Relationship among intra-abdominal pressure variation rate and severe pancreatitis severity and clinical prognosis

SANG Yunhua; GU Xin; LONG Hongjie

doi:10.3969/j.issn.1671-6450.2014.09.012

Abstract：Objective To explore the relationship among intra-abdominal pressure variation rate and severe pancreati-tis severity and clinical prognosis .Methods Selected 79 cases of patients with severe pancreatitis , intra-abdominal pressure ( IAP) were measured by indirect monitoring bladder pressure measurement , according to the score of acute physiology and chronic health evaluation (APACHEII), APACHEII ≥15 (median) were defined as the observation group with 40 cases, APACHEII<15 as the control group with 39 cases, intra-abdominal pressure level , Ranson score results were compared be-tween the 2 groups of patients , analyzed the relationship between intra-abdominal pressure variation rate , APACHEII, Ranson score and clinical prognosis .Results Intra-abdominal pressure peak value , Ranson score and organ dysfunction and mortality of observation group were significantly higher than those in the control group ( P <0.05);the Pearson correlation analysis re-vealed that intra-abdominal pressure variation rate was significantly and positively related to APACHEII score and Ranson score ( R =0.872, R =0.718, P <0.05), APACHEII was significantly and positively related to and Ranson score ( R =0.694, P <0.05);intra-abdominal pressure variation rate predictive value for mortality (area under the ROC curve) was 93.65%, slightly higher than the APACHEII score of 89.65%, no statistically significant difference between them were found ( P >0.05), and Ranson score’s predicting value was 82.24%, there were significant difference between intra-abdominal pressure variation rate and Ranson score ( P <0.05).Conclusion Along with intra-abdominal pressure variation rate increased , se-vere pancreatitis is more serious , and the prognosis gets worse .