Analysis of el ft bundle bra nch block impact on the prognosis of ischemic cardiomyopathy
FENG Tianjie
CHEN Keping
REN Xiaoqing
HUA Wei
ZHANG Shu
Abstract：Objective To observe the long term prognosis effect of complete left bundle branch block ( LBBB) on pa-tients with ischemic cardiomyopathy .Methods From 2004 January to 2009 December , 899 ischemic cardiomyopathy patients with left ventricular angiography confirmed LVEF≤35%were enrolled, the ECG examination confirmed the presence of bun-dle branch block in 25 cases ( group LBBB ) .Select the same period 48 ischemic cardiomyopathy patients without bundle branch block as the control group .Through inpatient medical records , follow-up, re-admission review , telephone follow-up to evaluate the prognosis of the patients .Results Drinking history of group LBBB was higher than the control group (32.0%vs. 14.6%).In LBBB group, the ratio of patients with anterior wall myocardial infarction history was significantly higher than the control group (88.0%vs.75.0%), left atrial echocardiographic diameter and left ventricular end diastolic diameter greater than the patients in the control group [(41.0 ±6.9) mm vs.(37.0 ±3.8) mm,(65.0 ±5.3) mm vs.(60.0 ±4.8) mm], the proportion of combined lesions in the anterior descending and circumflex branch was higher than the control group (16.0%vs.8.3%), the differences were statistically significant ( P <0.01).All-cause mortality, hemodynamic endpoints ratio in LBBB group was obviously higher than that in control group , the differences were statistically significant (12.0%vs.6.3%, 64.0%vs.27.1%, P <0.01).Cox regression analysis showed: anterior wall myocardial infarction , left bundle branch block are risk factors of heart failure death , readmission , ventricular arrhythmia , heart transplant composite endpoint in ische-mic cardiomyopathy patients (RR=1.04, RR=1.13, P <0.01).Conclusion Complete left bundle branch block is risk factor of adverse outcomes in ischemic cardiomyopathy patients with LVEF ≤35%, compared with patients without bundle branch block , occurrence of all-cause mortality , heart failure readmission , heart transplantation are significantly increased in ischemic cardiomyopathy patients with LBBB .
Keywords：Blockleft bundle branchCardiomyopathyischemicPrognosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 884-887,890 )