Clinical observation of Qiliqiangxin capsules improved vascular endothelial function on patients with chronic systolic heart failure
Abstract：Objective To observe Qiliqiangxin capsule on vascular endothelial function of patients with chronic heart failure.Methods 130 cases with chronic heart failure were randomly divided into control group (oral captopril tablets,12. 5mg/times, three times a day in the conventional therapy ) 60 cases, the treatment group (conventional treatment based on o-ral stilbene Lepidii cardiac capsules , 4/times, three times daily) in 70 cases, treatment for four weeks .Two groups of pa-tients before and after treatment were observed plasma endothelin (ET), nitric oxide (NO), calcitonin gene-related peptide (CGRP), and left ventricular ejection fraction (EF) and other indicators of change .Results Qiliqiangxin treatment group after 4 weeks of treatment, serum ET and NT-proBNP levels in patients decreased significantly ( t =6.530,26.862, P <0.01), NO, CGRP levels increased significantly ( t =5.955,9.748, P <0.05, P <0.01), significantly improved symp-toms of heart failure, the total efficiency of the treatment group was significantly better than the control group (χ2 =2.357, 2.589, P <0.05).Conclusion Qiliqiangxin capsules effectively protect endothelial function of patients with chronic systolic heart failure ,and improve heart failure symptoms and the degree of chronic heart failure .
Keywords：Qiliqiangxin capsulesHeart failurechronicsystolicVascular endothelial functionTotal efficiency
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 827-830 )