Relationship of serum Cys-C, homocysteine level and intima-media thickness in carotid artery atherosclerosis with a-cute cerebral infarction
FENG Min
JIAO Xianchun
SHEN Longshan
Abstract：Objective To investigate the correlation of serum cystatin C ( Cys-C) , the level of plasma homocysteine (Hcy) and carotid atherosclerosis (CAA) in acute cerebral infarction (ACI) patients'.Methods One hundred and twenty cases of cerebral infarction patients were enrolled as observation group , in the same period , 60 cases of non-cerebrovascular disease patients were enrolled as a control group .The serum Cys-C, three glycerol ( TG) , cholesterol ( TC) , low density lipo-protein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FPG), Hcy levels of the 2 groups were detected and compared , as well as used the color Doppler ultrasound to detect the carotid artery intima-media thick-ness (IMT).Results The observation group and the control group of serum Cys-C were (1.36 ±0.24) mg/L and (1.03 ± 0.13) mg/L, there was significant difference between the 2 groups ( P <0.01);TG, TC, LDL-C, HDL-C, FPG, Hcy level and carotid artery IMT were significant different between the 2 groups ( P <0.01).Serum Cys-C level and TC, TG, HDL-C, LDL-C, FPG are not correlated ( r =0.076, -0.158, -0.040, 0.012, -0.176, P >0.05) and blood Hcy and carotid artery IMT were significantly positive correlated ( r =0.871, 0.819, P <0.01).Conclusion High Cys-C level is an impor-tant risk factor of ACI , and was positively correlated with serum Hcy , and closely related to the formation of CAA .
Keywords：Cerebral infarctionacuteCystatin CHomocysteineCarotid atherosclerosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 793-795 )