The characteristics of serum lipids in activity rheumatoid arthritis
JIANG Yi
WANG Sikun
CHEN Su
HU Xiaojun
SUN Yueling
Abstract：Objective To observe the characteristics of serum lipids in activity rheumatoid arthritis ( RA) and inves-tigate its clinical significance.Methods Select active RA patients (active group) 40 cases, non-active RA patients (inactive group) 36 cases, and healthy control group of 30 patients, while the subjects serum total cholesterol ( TC), triglyceride (TG), high-density lipoprotein cholesterol ( HDL-C), low density lipoprotein cholesterol ( LDL-C), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB) and C reactive protein (CRP), rheumatoid factor (RF), erythrocyte sedimentation rate (ESR) were detected.Results Compared with the healthy control group , two groups of RA patients'HDL-C, ApoA1 de-creased significantly ( P <0.01), ESR,CRP,RF increased significantly( P <0.01),and the active group changed more ob-vious than the inactivity group ( P <0.01) , and TC, TG, LDL-C, ApoB in 3 groups showed no statistically significant ( P >0.05);HDL-C, ApoA1 presented significant negative correlation with CRP , ESR, RF ( r =-0.634, r =-0.901, r =-0.485, r =-0.625, r =-0.520, r =-0.236, P <0.05 or P <0.01); TC, TG, LDL-C, ApoB and disease activity was not significant correlated ( P >0.05).Conclusion In the active phase of RA, serum HDL-C and ApoA1 levels decrease significantly, this change is closely related with the disease activity .
Keywords：ArthritisrheumatoidSerum lipidSerum lipids
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 497-499 )