The effects of zedoary turmeric oil injection combined with conventional chemotherapy on life quality of the patients with early stage ovarian cancer
LIANG Dan
YANG Meichun
LIN Zhong
LI Lin
LI Min
FANG Gang
Abstract：Objective To investigate the effects of zedoary turmeric oil injection combined with conventional chemo -therapy on life quality of the patients with early stage ovarian cancer .Methods 62 cases of the patients with diagnosis as early ovarian cancer by pathology or cytology methods during 2010 September to 2012 December were randomly divided into the ob-servation group and the control group .The patients in the two groups were treated with docetaxel and cisplatin regimen in chemotherapy , at the first days , eighth days and fifteenth days , intravenous infusion of docetaxel 75 mg/m2 was applied;from the first day to the third day , intravenous infusion of cisplatin 30 mg/m2 was applied , every 21 d were taken as 1 cycles.The patients in the observation group were treated with combined zedoary turmeric oil injection (400 mg in0.9%sodium chloride solution 500 ml, intravenous drip , and one time per day ) .Based on the therapy as above , the change of the body weight , ap-petite, and Karnofsky scores of the patients in the two groups were observed and the adverse reactions were recorded .Rseul ts In the observation group, the appetite of 18 cases (58.1%) increased, the weight of 21 cases (67.8%) were gained, Karnofsky scores of 17 cases had an elevation more than 10 points (54.8%); in the control group, the appetite of 7 cases (22.6%) increased, the weight of 7 cases (22.6%) were gained, Karnofsky scores of 7 cases had an elevation more than10 points (22.6%) and there was significant difference between the two groups ( P <0.05).The gastrointestinal reaction , bone marrow inhibition degrees of the patients in the observation group was lower than those of the control group (58.07% vs. 67.74%,19.36%vs.29.03%), the difference was statistically significant ( P <0.05).Conclusion Zedoary turmeric oil injection can significantly reduce the adverse reaction of chemotherapy and improve the life quality of the in patients .
Keywords：Ovarian cancerChemotherapyZedoary turmeric oil injectionLife quality
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 448-450 )