The effect of emergency PCI combined IABP therapy on the levels of inflammatory factors in postoperative patients with AMI complicated by cardiogenic shock
WEN Zhiyong
HU Dongfang
LIU Xiaodong
Abstract：Objective To investigate the effect of emergency percutaneous coronary intervention ( PCI)treatment of intra-aortic balloon counterpulsation ( IABP) on the levels of inflammatory factors in postoperative patients with acute myocar -dial infarction ( AMI) complicated by cardiogenic shock .Methods 46 cases of observation group were AMI patients with car-diogenic shock , IABP support for application of emergency PCI for the treatment , during the same period , 32 cases of patients with AMI complicated by cardiogenic shock as the control group did not apply to the use of IABP support received the treat -ment of primary PCI , preoperative , after 3 and 7 d, C-reactive protein ( CRP) , tumor necrosis factor-α( TNF-α) , interleu-kin-6 (IL-6) were observed, preoperative and 2 weeks postoperative, three months after treatment, left ventricular ejection fraction when LVEF changes and patient mortality were observed .Results Observation group and control group in AMI classi-fication, lesion location , number of lesions involving the branches and stent implantation showed relatively no significant difference ( P >0.05), observation group showed shorter hospital stay than the control group ( P <0.05); The patients IABP average of (84.12 ±34.74) h, 2 groups preoperative CRP , TNF-α, IL-6 levels and LVEF was not significant differ-ence ( P >0.05), after 3 and 7 d, 2 groups'CRP, TNF-α, IL-6 levels were elevated ( P <0.05), but the observation group was significantly lower than the control group ( P <0.05), after 2 weeks, 3 months LVEF of the observation group was significantly higher ( P <0.05), mortality within 3 months after treatment, the observation group was significantly lower than the control group (30.43%vs.56.25%, P <0.05).Conclusion AMI patients with cardiogenic shock treated with PCI at the time of the emergency joint IABP therapy can significantly reduce postoperative inflammatory cytokine levels , improve left ventricular function and reduce postoperative mortality .
Keywords：Myocardial infarctionacuteShockcardiogenicPercutaneous coronary interventionIntra-aortic balloon counterpulsationInflammatory cytokines
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 358-360,364 )