The effect of Yangzhengxiaoji capsule on life quality after transcatheter arterial chemoembolization of HCC
FENG Jingjian
TAN Junli
GUO Yan
WANG Guifa
ZHAO Jingxia
WU Xiaoliang
WANG Xiaoyan
GAO Tong
Abstract：Objective To observe the effect of Yangzhengxiaoji capsule on quality of life in hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).Methods 60 patients with primary liver cancer were random-ly divided into control group and the treatment group with 30 patients in each group , control group only accept TACE .In treat-ment group, patients received TACE +Yangzhengxiaoji capsule;treatment lasted 28 d.Preoperative and postoperative QOL using the core scale ( QLQ-C30) assesses five functional areas , three main symptoms areas and six individual entries .Rseults Two cases were removed in treatment group and control group excluded three cases ,treatment groups'clinic benefit ( CB) rate was 89.3%(25/28), the control group's CB rate was 92.6%(25/27), the difference was not statistically significant ( P >0.05).2 groups of patients function scores showed no significant difference ( P >0.05).In the treatment group, fatigue, nausea, vomiting, pain, sleep disorders, loss of appetite, diarrhea score significantly improved compared with before treat-ment ( P <0.05, P <0.01).In control group, only fatigue, loss of appetite were improvement than before treatment ( P <0.05).Control group's fatigue, nausea, vomiting,pain,sleep disorders, loss of appetite, diarrhea scores were decreased 7.83%,4.01 %2,.78%,7.41%,7.41%,2.74%,the treatment group decreased by 11.91%,5.07%, 13.99%,15.47%, 15.47%,9.53%,improvement in the treatment group was more significantly than the control group ( P <0.05).TACE post-operative bone marrow suppression , WBC lower than the control group treated group ( P <0.05), ALT, AST 2 group differ-ence was also statistically significant ( P <0.05).Conclusion Yangzhengxiaoji capsule can significantly improve quality of life in hepatocellular carcinoma after transcatheter arterial chemoembolization .
Keywords：Yangzhengxiaoji capsuleHepatocellular carcinomaprimaryTranscatheter arterial chemoembolizationQuality of life
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 349-353 )