Effect of Lianhuaqingwen capsule on acute upper respiratory infection and their impact on the IFN- γ
WEI Mei
SONG Yuxun
ZHOU Hong
Abstract：Objective To evaluate the efficacy and safety of Lianhuaqingwen capsule in the treatment of acute upper respiratory infection and observe the effect on interferon gamma ( IFN-γ) of patients .Methods 203 cases of acute upper re-spiratory tract infection were randomly divided into two groups , treatment group of 101 cases (oral Lianhuaqingwen capsules), 102 cases in the control group given azithromycin tablets .To compare the efficacy of two groups , while the two groups were each randomly selected 20 cases of venous blood before and after each treatment , the application of ELISA kits to detect the concentration of serum IFN-γ.Results Overall efficacy in the treatment group effectiveness , efficiency and the temperature drops various clinical symptoms and signs of improvement rates were higher , two groups of patients in the prevalence of serum IFNγlevels were significantly higher , decreased significantly after treatment , with the treatment group decreased more signifi-cantly ( P <0.05).After treatment, two group patients'WBC and neutrophil percentage were significantly decreased ( P <0.05), but between the two groups , the difference was not statistically significant ( P >0.05).The incidence of adverse re-actions was not significant difference ( P >0.05 ) .Conclusion Lianhuaqingwen capsule can relieve a variety of clinical symptoms of acute upper respiratory tract infection , and have some anti-inflammatory antiviral activity .
Keywords：Lianhuaqingwen capsuleUpper respiratory tract infectionacuteIFN-γ
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 345-348 )