Therapeutic effect of Qiliqiangxin capsule on the treatment of chronic renal insufficiency heart failure patients
LIU Lingxi
WU Zhihui
ZHU Xiaogang
Abstract：Objective To explore the Qiliqiangxin capsule for the treatment of chronic renal insufficiency ( CRF) pa-tients with congestive heart failure ( CHF) with curative effect and application value .Methods Select 60 cases of patients with CHF with CRF, patients were randomly divided into observation group and control group (30 cases in each group), two groups were given conventional treatment , the observation group add Qiliqiangxin capsule orally, after 12 weeks of treatment, observation of patients before and after treatment serum creatinine (SCr), urea nitrogen (BUN), plasma amino terminal brain natriuretic peptide precursor (NT-proBNP), 24 h urine protein and left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDD), cardiac output (CO) change, TCM symptoms change.Results Two groups after treatment SCr, BUN, NT-proBNP, 24 h urinary protein decreased than before treatment ( P <0.05), the observation group decreased more significantly than in the control group ( P <0.05); after treatment LVEF, CO were raised than before treatment , LVEDD decreased ( P <0.05), the observation group improved more significantly than the control group ( P <0.05);ob-servation group total effective rate were 76.67%, higher than that of control group of 46.63%( P <0.05);digoxin average amount of observation group (0.114 ±0.053) mg/d, less than the control group (0.235 ±0.068) mg/d ( P <0.05). Conclusion Qiliqiangxin capsule assisted treatment CRF with CHF , can significantly improve cardiac function in patients with renal function and reduce the dose of digitalis preparations .
Keywords：Renal insufficiencychronicHeart failureQiliqiangxin capsule
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 342-344 )