The therapeutic effect of Qiliqiangxin capsule on chronic heart failure in very elderly patients
GE Liang
WANG Hua
MA Chunwei
Abstract：Objective To evaluate the clinical efficacy of Qiliqiangxin capsule and safety on very elderly patients with chronic heart failure , and provide the basis for rational drug use .Methods 60 patients who were ≥80 year old with chronic heart failure were enrolled and randomly divided into control group and the treatment group , 30 cases in each group .2 groups were given diuretics , metoprolol succinate extended release tablets ( metoprolol ) or digoxin and other conventional western medicine, treatment group plus Qiliqiangxin capsule, 3 times a day.After 8 weeks of treatment, observed the clinical efficacy of serum brain natriuretic peptide ( BNP) and cardiac color Doppler echocardiography cardiac function index ( CI, LVEF, SV, CO) , and observed adverse reactions .Results In treatment group after treatment , the total effective rate was 93.33%(28/30), higher than control group of 73.34%(22/30), the difference was statistically significant ( P <0.05). BNP levels in the two groups after treatment were reduced than before treatment ( P <0.05), the treatment group compared with the control group, BNP levels decreased more significantly ( P <0.05).After treatment, HR, SV, CO, CI, LVEF val-ues of the two groups were improved than before treatment ( P <0.05), but no difference between the two groups was statisti-cally significant ( P >0.05).Both two groups found no serious adverse events .Conclusion Qiliqiangxin capsule clearly assisted treatment of chronic heart failure efficacy , safety, and can be used in very elderly patients with chronic heart failure .
Keywords：Qiliqiangxin capsuleVery elderlyHeart failurechronicClinical research
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 339-341 )