Clinical observation on effect of Tongxinluo capsule in treating vascular dementia
LIU Shuangxiu
GUO Hezong
FENG Shufeng
YANG Wansheng
ZHANG Jing
Abstract：Objective To study the effect of Tongxinluo capsule in treating vascular dementia .Methods 70 patients selected according to the diagnostic standard of American Association of Psychiatry were randomly divided into treatment group and control group , 35 patients in treatment group were given Tongxinluo +Naofukang and Naofukang respectively ,the thera-peutic course was 3 months.Changes of clinical symptoms ,mini-mental state examination (MMSE) and activity of daily living (ADL) score,brain electrical activity mapping,platelet aggregation and blood lipid were observed .Results Total effective rate of clinical symptoms in the treated group was 88 .57% and brain electrical activity mapping markedly effective rate was 62.86%,which was 62.86%and 45.74%in control group respectively( P <0.05).Compared with pretreatment,the MMSE and ADL score increased in both groups( P <0.01),the treatment group were superior to those in control group ( P <0.05). the whole blood viscosity, plasma viscosity in control group was improved ( P <0.01, P <0.05), the whole blood viscosity, plasma viscosity,fibrinogen,TC,TG,LDL-C were improved in treatment group ( P <0.01),the changes of low shear viscosity , plasma viscosity,TC,TG,LDL-C in treatment group was more obvious than control group ( P <0.05, P <0.01).Conclusion Tongxinluo is an effective drug which could improve cognitive function ,daily life activity and clinical symptoms in patients with DV.
Keywords：Tongxinluo capsuleVascular dementiaClinical effects
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 336-338 )