Correlation Analysis of Serological Indicators and Severity of Infection with Novel Coronavirus(COVID-19)Infection
Ren Bingye
Zhaxi Yangzong
Shi Li
Abstract：Objective To compare the general hematological indicators of COVID-19 infection between plateau and plain areas,as well as the first and second infections of COVID-19,and to discuss the correlation between common serological indicators and severity of illness.Methods A total of 708 patients with positive nucleic acid tests who vis-ited the outpatient clinic of the hospital from December 2022 to July 2023 were collected.The patients were divided into mild and moderate-to-severe groups according to their conditions.The general clinical data and serological relat-ed indicators were compared after grouping,and the relevant factors affecting the classification were analyzed.Results There were statistically significant differences between the mild and the moderate-to-severe in terms of age,platelets,neutrophil ratio,and D-dimer.There were no statistically significant differences in altitude,ethnicity,num-ber of infections,gender,total number of white blood cells,monocytes,lymphocytes,CRP,PCT and NLR between the two groups.Conclusion Age,platelets,neutrophil ratio,and D-dimer are risk factors for severe disease in COV-ID-19 infection,and anticoagulation or antiplatelet therapy should be given as soon as possible.
Keywords：Plateau areaNovel coronavirusRisk factors
Publication Date：2025-01-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 51-56 )