Summary of the best evidence for the management of deep vein thrombosis of lower extremities during the perioperative period of liver cancer
WANG Xinmiao
MI Yuanna
GAN Zhe
LIAO Bizhen
Abstract：Objective:To retrieve,organize,and synthesize evidence on the management of perioperative deep vein thrombosis(DVT)of the lower extremities in patients with liver cancer,providing a reference for clinical practice in this area.Methods:A comprehensive search was conducted using the"6S"evidence-based pyramid model across BMJ Best Practice,UpToDate,Cochrane Library,PubMed,CBM and so on.The search period was from January 2019 to December 2024.Search content included guidelines,systematic reviews,evidence summaries,and clinical practice.A total of 3 trained researchers independently assessed quality using standardized tools,then extracted and synthesized evidence according to established consensus.Results:A total of 13 articles were ultimately included,comprising 8 guidelines,2 systematic reviews,2 evidence summaries,and 1 clinical practice.The final evidence encompassed 21 pieces of best evidence across 7 dimensions,including risk factor control,assessment,primary prevention,mechanical prevention,pharmacological prevention,health education,and team training.Conclusion:Management of perioperative DVT of lower extremities in patients with liver cancer requires comprehensive consideration of surgical type,individual risk,and postoperative recovery.Implementing multi-tiered prevention and treatment measures optimizes perioperative DVT management strategies,effectively reducing perioperative incidence of DVT of lower extremities and improving patient outcomes.
Keywords：liver cancerperioperative perioddeep vein thrombosis of lower extremitiesevidence-based nursingevidence summary
Publication Date：2026-02-25
Online Publishing Date：2026-03-16(First online date of this platform, not the publication date of the document)
Pages：7( 687-693 )