Early evaluation and preventive management of intensive care unit-acquired weakness in adults:a summary of the best evidence
YANG Xia
DUAN Pengcheng
LING Donglan
YU Tingting
LU Murong
Abstract：Objective:To select and summarize the best evidence for early evaluation and preventive management of intensive care unit-acquired weakness(ICU-AW)in adults,and provide an evidence-based basis for further standardization of clinical practice.Methods:According to the"6S"evidence pyramid model,the evidence including clinical decision-making,best practices,clinical guidelines,evidence summary,systematic review,Meta-analysis,expert consensus,and randomized controlled trials(RCTs)were retrieved from evidence-based resource database,guideline database,relevant professional database,and original research database from top to bottom.The search period limit was from the establishment of the database to January 14,2025.Two master's students who had received a series of training in evidence-based research evaluated the quality of the included literature.Then they extracted and integrated the evidence.Results:A total of 18 articles were included,including 4 clinical decision-making,6 guidelines,3 expert consensus,3 systematic reviews,1 Meta-analysis,and 1 RCT.A total of 25 pieces of evidence were summarized in four aspects:assessment timing,assessment content and methods,risk factor assessment,and preventive management measures.Conclusions:The best evidence summarized in this study provides a basis for the early assessment and preventive management of adult ICU-AW.When converting evidence,clinical medical staff should combine patients'characteristics and application scenarios to further standardize the early assessment and management process of adult ICU-AW patients,so as to improve the clinical outcomes of patients with ICU-AW.
Keywords：intensive care unit-acquired weaknessICU-AWassessmentmanagementbest evidenceevidence summaryevidence-based nursing
Publication Date：2025-07-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：9( 2585-2593 )