Evidence map analysis of non-pharmacological interventions for postoperative pain in patients undergoing total knee arthroplasty

FAN Meng; SUN Yiyun; YAO Yaji

doi:10.12102/j.issn.2095-8668.2025.11.007

Abstract：Objective:To systematically describe and evaluate studies on non-pharmacological interventions for postoperative pain in patients undergoing total knee arthroplasty using evidence mapping.Methods:CNKI,WanFang Database,VIP,CBM,PubMed,Web of Science,the Cochrane Library,and EMbase were searched by computer from the establishment of the database to July 25,2024,to obtain a systematic review/Meta-analysis of non-pharmacological interventions for postoperative pain in patients undergoing total knee arthroplasty.The systematic review evaluation tool AMSTAR 2 was used to evaluate the quality of the included studies,and the evidence map was used to comprehensively present the relevant information of the included studies.Results:A total of 40 articles were included.Among the non-drug interventions,traditional Chinese medicine therapy accounted for a large proportion,followed by cryotherapy.According to the results of the AMSTAR 2 quality assessment scale,the methodological problems included the failure to not write a plan in advance,to list the list of excluded literatures and the reasons for exclusion,and lack of funding information.The results of the evidence map showed that among the included 40 studies,3 studies concluded that it was beneficial,26 studies concluded that it might be beneficial,9 studies concluded that there was no difference in effect,and 2 studies concluded that it was uncertain.Conclusion:Current evidence shows that non-pharmacological interventions for postoperative pain in patients undergoing total knee arthroplasty are effective,but the quality of methodology needs to be improved.It is recommended to carry out higher quality and standardized research to provide evidence-based basis.