Development and reliability and validity test of symptom cluster assessment scale for patients with secondary hyperparathyroidism in uremia

DENG Zhuozhou; YANG Yuewen; SHEN Wei

doi:10.12102/j.issn.2095-8668.2024.21.006

Abstract：Objective:To develop a symptom cluster assessment scale for patients with secondary hyperparathyroidism(SHPT)in uremia and test its reliability and validity,so as to provide a reference for medical staff to assess the symptoms of SHPT patients in uremia.Methods:Based on the unpleasant symptom theory,the symptom cluster assessment scale for SHPT patients in uremia was determined by literature retrieve,semi-structured interview,Delphi method,pre-investigation,reliability test,and validity test.Results:A total of 29 items from 6 dimensions in the symptom cluster assessment scale for SHPT patients in uremia,including digestive and excretion symptom cluster,skin-related symptom cluster,cognitive symptom cluster,psychological-sleep symptom cluster,activity limitation symptom cluster,and systemic manifestation symptom cluster.The Cronbach's α coefficients were 0.869,0.839,0.879,0.827,0.884,0.864,respectively.The content validity of each item was 0.855-0.903,and the total content validity of the scale was 0.878.The exploratory factor results showed that the factor loading of each measurement item was＞0.5,and the cross loading was＜0.4.The confirmatory factor analysis results showed that the fitting indexes meet the standards of general structural equation model(SEM)research,and the model fit was good.The correlation coefficients of each dimension were 0.401-0.543.Conclusions:The symptom cluster assessment scale for SHPT patients in uremia is scientific and practical,with high reliability and validity,which can provide a reference for medical staff to evaluate the symptoms of SHPT patients in uremia.