Risk factors of multidrug-resistant bacteria infection in ICU patients:a Meta-analysis
YAO Yufei
SUN Haichao
HU Yi
Abstract：Objective:To systematically evaluate the risk factors for the development of multidrug-resistant organism(MDRO)infections in ICU patients.Methods:Computer searched of publicly available studies on risk factors for MDRO infection in ICU patients on CNKI,WanFang Database,VIP,CBM,PubMed,EMbase,the Cochrane Library,Web of Science,and CIHANL.The data of the included literature were extracted,the Newcastle-Ottawa Scale(NOS)was used to evaluate the quality of the included literature,and RevMan 5.4.1 was used for Meta-analysis.Results:A total of 30 articles with 18 302 patients were included.Meta-analysis results showed that APACHE Ⅱ score,antibiotic therapy,diabetes mellitus,chronic lung disease,mechanical ventilation,duration of ICU stay,duration of indwelling catheterization,and central venous placement were risk factors for MDRO infection in ICU patients(P＜0.05).Conclusion:Current evidence shows that there are many risk factors for MDRO infection in ICU patients,and targeted preventive and control measures should be taken to reduce the occurrence of MDRO infection according to the different conditions of patients.
Keywords：intensive care unitICUmultidrug-resistant organismMDROinfectionrisk factorsMeta-analysis
Publication Date：2024-08-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 2673-2680 )