Hemostatic effect of chitosan hemostatic pad on coronary interventional therapy after transradial artery:a Meta-analysis
QI Shuming
WU Zhenzhen
LYU Qian
YE Hongjiang
KONG Yue
Abstract：Objective:To evaluate the hemostatic effect of chitosan hemostatic pads after coronary intervention(TRI)via radial artery through Meta-analysis.Methods:The literatures on the application of chitosan hemostatic pad in patients after TRI were retrieved from CNKI,WanFang Database,VIP,PubMed,the Cochrane Library,Web of Science,etc.Literature selection,quality evaluation and data extraction were conducted independently by two researchers in strict accordance with inclusion and exclusion criteria.RevMan 5.4 software was used for Meta-analysis.Results:A total of 9 articles were included,involving 5 443 patients,including 2 727 patients in the experimental group and 2 716 patients in the control group.The results of Meta-analysis showed that compared with conventional care,chitosan hemostatic pad could effectively shorten the hemostatic time of postoperative TRI patients(SMD=-2.63,95％CI-3.94--1.32,P＜0.000 1),and reduce the incidence of radial artery occlusion(OR=0.63,95％CI 0.46-0.85,P=0.003)and forearm hematoma(OR=0.37,95％CI 0.27-0.50,P＜0.000 01),with statistical significance.Conclusion:The available evidence shows that compared with conventional treatment,chitosan hemostatic pad can effectively shorten the hemostatic time of patients after transradial artery TRI,reduce the incidence of radial artery occlusion,forearm hematoma and other complications.
Keywords：chitosan hemostatic padtransradial coronary interventionhemostatic effectMeta-analysisevidence-based nursing
Publication Date：2024-05-31
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1756-1761 )