Efficacy of the application of Nasojejunal Feeding and Nasogastric Feeding in critically ill ICU patients:Meta-analysis and systematic review
Abstract：Objective:To evaluate the application effect of nasojejunal feeding and nasogastric feeding for critically ill ICU patients.Methods:The randomized controlled trials(RCTs) related to nasojejunal feeding and nasogastric feeding in ICU patients were collected from PubMed,Embase,Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang Database and China full-text database(VIP).Meta-analysis was conducted for these literatures by using the software RevMan 5.3.Results:22 articles were involved totally 1 498 patients are included.The Meta-analysis showed that time to reach the required nutrition[WMD=-84.84,95%CI(-95.19,-74.49),P<0.000 01],incidence of gastric retention[RR=0.16,95%CI(0.09,0.29),P<0.000 01],the incidence of reflux and aspiration[RR=0.18,95%CI(0.10,0.32),P<0.000 01],the incidence of aspiration pneumonitis[RR=0.44,95%CI(0.28,0.70),P=0.000 5],and length of ICU stay lower that in NGF group[WMD=-2.69,95%CI(-4.24,-1.13),P=0.000 7],but NJF increased the rates of gastrointestinal bleeding[RR=2.26,95%CI(1.10,4.65),P=0.03].Conclusions:Nasojejunal feeding in critically ill ICU patients could increase the efficiency of nutrition intake and reduce the complications.But it easily lead to gastrointestinal bleeding,still need more high-quality,large sample study further confirmed.
Keywords：nasojejunal feedingnasogastric feedingICUcritically ill patientsMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 198-204 )