Progress on non-invasive electrical and magnetic neuromodulation therapy for cognitive impairment in posttraumatic stress disorder
JIN Zhuo
REN Xiao-xin
WANG Hao-ting
QIAO Yi-jing
ZHAO Yu-chao
ZHENG Chen-guang
Abstract：Posttraumatic stress disorder(PTSD)is a severe mental disorder triggered by traumatic events.Its core clinical symptoms include intrusive memories,avoidance behaviors,negative alterations in mood and cognitive disorder,and hyperarousal.These symptoms are closely associated with aberrant neural circuitry involving the amygdala,hippocampus and prefrontal cortex.However,current pharmacological and psychological interventions are constrained by limited efficacy,poor compliance,and undesirable side effects.Given the high safety,strong reproducibility,and high patient acceptance,non-invasive electrical and magnetic neuromodulation techniques have emerged as a research focus for improving cognitive impairment in PTSD.This paper reviews the advancements in applying transcranial electrical stimulation(TES)and transcranial magnetic stimulation(TMS)to alleviate cognitive impairment in PTSD,and discusses the potential value of their combined use with psychological therapies.It aims to provide new perspectives for the clinical application of neuromodulation technique in treating cognitive impairment in PTSD.
Keywords：Stress disorderspost-traumaticCognition disordersElectric stimulation therapyTranscranial magnetic stimulationReview
Publication Date：2026-01-25
Online Publishing Date：2026-04-07(First online date of this platform, not the publication date of the document)
Pages：10( 30-39 )