Progress on the application of growth hormone in traumatic brain injury
LIAO Xi-xian
MEI Fen
QIU Bing-hui
QI Song-tao
ZHONG Qing-lei
BAO Yun
Abstract：Pituitary dysfunction after traumatic brain injury(TBI)has increasingly attracted attention,with growth hormone deficiency(GHD)being the most common subtype.The use of growth hormone(GH)replacement therapy for patients with GHD after TBI has a positive impact on prognosis,including cognitive improvement,and so on.This article reviews the mechanisms of pathophysiology of GHD,the mechanisms of GH treatment for TBI and the current status of clinical application,and proposes future development directions to provide the theoretical guidance for the application of GH in the treatment of GHD after TBI.
Keywords：Brain injuriestraumaticHypopituitarismGrowth hormoneReview
Publication Date：2025-09-25
Online Publishing Date：2025-10-28(First online date of this platform, not the publication date of the document)
Pages：9( 798-806 )