Analysis of risk factors for new-onset ischemic stroke after Sun's procedure in patients with acute type A aortic dissection
ZHANG Chen-yu
ZHANG Shao-peng
LI Pei-quan
BAI Yun-peng
CHEN Tong-yun
CHEN Qing-liang
Abstract：Objective To investigate the risk factors of new-onset ischemic stroke in patients with acute type A aortic dissection(ATAAD)undergoing Sun's procedure.Methods A total of 147 patients with ATAAD who underwent Sun's procedure between January 2015 and May 2024 in Chest Hospital,Tianjin University were included.Patients were divided into new-onset ischemic stroke group(n=21)and no new-onset ischemic stroke group(n=126)based on whether they had newly developed ischemic stroke after surgery.Univariate and multivariate Logistic regression analyses were used to screen for the risk factors of new-onset ischemic stroke after Sun's procedure.Results Logistic regression analysis showed that preoperative stroke(OR=14.731,95%CI:1.740-124.727;P=0.014),elevated preoperative serum creatinine level(OR=1.023,95%CI:1.009-1.038;P=0.002),preoperative New York Heart Association(NYHA)functional class Ⅲ-Ⅳ(OR=8.054,95%CI:2.393-27.111;P=0.001),and incomplete Willis'circle of type C(OR=33.575,95%CI:1.283-878.921;P=0.035)and type D(OR=5.734,95%CI:1.105-29.765;P=0.038)were risk factors for the new-onset ischemic stroke after Sun's procedure in patients with ATAAD.Conclusions Preoperative stroke,elevated preoperative serum creatinine level,NYHA class Ⅲ-Ⅳ,and incomplete Willis'circle of type C and D were risk factors for the new-onset ischemic stroke after Sun's procedure in patients with ATAAD.
Keywords：Aortic diseasesAneurysmdissectingPostoperative complicationsIschemic strokeRisk factorsLogistic models
Publication Date：2025-08-25
Online Publishing Date：2025-09-22(First online date of this platform, not the publication date of the document)
Pages：9( 739-747 )