Research progress of rehabilitation therapy in Parkinson's disease and its mechanism
LIU Jin
YANG Xin-xin
XIANG Jie
Abstract:Parkinson's disease (PD) is characterized by the progressive degeneration of dopaminergic neurons in substantia nigra pars compacta.Rehabilitation therapy can delay the development of disease,improve motor symptoms and non-motor symptoms (NMS),and consequently improve the activities of daily living (ADL) in patients with PD.The mechanism of rehabilitation improving the symptoms of PD is very complex,involving a variety of molecular mechanisms.Thus,this review will focus on the effect of rehabilitation therapy on PD and the underlying molecular mechanism including neurotransmitters,trophic factors,synaptic plasticity and immune system.
Keywords:Parkinson discaseRehabilitationReview
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:6( 403-408 )