DOI: 10.12307/2026.625
Meta-analysis of the clinical efficacy of high-intensity interval exercise and middle-intensity continuous training in patients with coronary heart disease
Hu Yujie
Xie Ping
Lu Weijie
Yang Kang
Deng Yaoting
Liu Mengyang
Abstract：OBJECTIVE:Although existing studies have suggested that high-intensity interval training may be more effective than moderate-intensity continuous training in improving cardiopulmonary function in patients with coronary heart disease,its clinical efficacy remains controversial.Therefore,this meta-analysis aims to systematically evaluate the clinical efficacy of high-intensity interval training versus moderate-intensity continuous training in patients with coronary heart disease.
METHODS:Randomized controlled trials of high-intensity interval training and moderate-intensity continuous training in cardiac rehabilitation of coronary heart disease were included by searching Chinese and English databases such as CNKI,WanFang Database,Wipro,PubMed,Cochrane Library,Embase,and Web of science.Meta-analysis of the final included literature was performed using Review Manager 5.3 and StataMP 17.
RESULTS:A total of 10 studies met the study criteria and included 773 patients.Compared with moderate-intensity continuous training,high-intensity interval training resulted in higher peak oxygen uptake and oxygen uptake at the first ventilatory threshold were higher[mean difference=1.30,95％confidence interval(0.71,1.89),P<0.000 1;mean difference=1.54,95％confidence interval(0.56,2.53),P=0.002].Both groups showed no significant difference in resting systolic blood pressure,resting diastolic blood pressure,resting heart rate and peak heart rate(P>0.05).
CONCLUSION:Compared with moderate-intensity continuous training,high-intensity interval training is more advantageous in improving peak oxygen uptake and oxygen uptake at the first ventilation threshold in coronary artery disease,while has no significant effects on resting heart rate,peak heart rate,resting systolic blood pressure,and resting diastolic blood pressure.
Keywords：coronary heart diseasehigh-intensity interval exercisemoderate-intensity aerobic exercisecardiac rehabilitationclinical efficacyrandomized controlled trialmeta-analysis
Publication Date：2026-04-08
Online Publishing Date：2026-03-18(First online date of this platform, not the publication date of the document)
Pages：10( 2584-2593 )