Meta-analysis of lumbar bone mineral density,pain score and fall incidence in middle-aged and elderly osteoporosis patients undergoing whole-body vibration training

Ren Pengbo; Li Tingwen; Cai Feng; Zhang Jian

doi:10.12307/2026.634

Abstract：OBJECTIVE:Numerous studies have confirmed that whole-body vibration training has a definite therapeutic effect on osteoporosis,effectively improving balance function and enhancing prognostic quality in such patients.Herein,we systematically evaluate the effects of whole-body vibration training on lumbar bone density,pain scores,and fall incidence rates in patients with osteoporosis. METHODS:The databases of PubMed,EMBASE,ScienceDirect,Cochrane Library,CNKI,VIP and WanFang Data,and China Biology Medicine(CBM)were searched by computer to screen out randomized controlled trials of middle-aged and elderly patients with osteoporosis who underwent whole-body vibration training.The trial group received whole-body vibration training,and the control group received only additional treatment or no intervention.The literature search was conducted using a combination of free terms and subject headings,and the search terms included"whole-body vibration training,""middle-aged and elderly,""quinquagenarian,""osteoporosis,""vibration therapy,""mechanical vibration,""visual analogue scale score,"and"fall incidence rates."The retrieval period covered from the inception of each database to December 2024.Meta-analysis was performed using RevMan 5.3 statistical software. RESULTS:This meta-analysis included 10 randomized controlled trials with a total of 656 patients.The analysis results showed no statistically significant differences in lumbar bone mineral density[mean difference(MD)=0.01,95%confidence interval(CI):-0.01 to 0.04,P=0.22],radial trabecular volumetric bone mineral density[MD=-0.87,95%CI:-2.93 to 1.20,P=0.41],and tibial trabecular volumetric bone mineral density[MD=0.34,95%CI:-0.69 to 1.38,P=0.52]between the two groups.However,the whole-body vibration training group had a significantly lower visual analog scale score[MD=-1.48,95%CI:-2.91 to-0.05,P=0.04]and a lower fall incidence rate compared to the control group[odds ratio=0.52,95%CI:0.29 to 0.92,P=0.03]. CONCLUSION:Whole-body vibration training can significantly alleviate pain and reduce the incidence of falls in middle-aged and elderly patients,but the effect of improving lumbar bone mineral density is not obvious,and more research and follow-up with higher quality and longer intervention time are needed to further verify the conclusion.