Preparation and characterization properties of three different ratios of biphasic calcium phosphate

Shao Ziyu; Li Qian; Qumanguli·Abudukelimu; Han Youjun; Hu Yang

doi:10.12307/2026.604

Abstract：BACKGROUND:Root canal sealers,which are widely used in current clinical practice,still have the disadvantages of poor biocompatibility and poor degradability. OBJECTIVE:To prepare nanohydroxyapatite and β-tricalcium phosphate biphasic calcium phosphate composites with polyvinyl alcohol as the binder and characterize the properties of the composites. METHODS:15%polyvinyl alcohol hydrogel was mixed with different proportions of nanohydroxyapatite and β-tricalcium phosphate(the mass ratio of nanohydroxyapatite to β-tricalcium phosphate was 30:70,40:60,and 50:50,respectively).Biphasic calcium phosphate/polyvinyl alcohol composites were prepared by freeze drying.30%nanohydroxyapatite/polyvinyl alcohol composites and 30%β-tricalcium phosphate/polyvinyl alcohol composites were prepared at the same time.Scanning electron microscope,X-ray energy dispersive spectroscopy,X-ray diffractometer,X-ray photoelectron spectroscopy,and Fourier infrared spectroscopy were used to characterize the physical and chemical properties of each group of composites.The mechanical properties of each group of composites were studied by universal mechanical testing machine. RESULTS AND CONCLUSION:(1)Scanning electron microscopy and X-ray energy dispersive spectroscopy showed that nanohydroxyapatite and β-tricalcium phosphate in the biphasic calcium phosphate/polyvinyl alcohol composites were clustered together,and the C,O,Ca,and P elements were evenly distributed.(2)X-ray diffraction,X-ray photoelectron spectroscopy,and Fourier transform infrared spectroscopy results of the biphasic calcium phosphate/polyvinyl alcohol composites showed that polyvinyl alcohol was successfully mixed with nanohydroxyapatite and β-tricalcium phosphate without chemical structure changes.(3)There were no significant differences in the ultimate compressive strength and elastic modulus of the five groups of composites(P>0.05),among which the elastic modulus of the biphasic calcium phosphate(40:60)/polyvinyl alcohol composite was the largest.