Antimicrobial modification for orthopedic metal implants:merits and demerits
Luo Jin
Lan Hai
Abstract：BACKGROUND: Infection of orthopedic implants is a problem to be solved. Currently, scholars are trying to endow orthopedic implants with an anti-infection function, and the research on antibacterial activity of implants has been a hot topic. OBJECTIVE: To introduce the modification methods of orthopedic metal implants in recent years. METHODS: Science Direct online (2015-2019) , WanFang (2015-2018) and VIP (2015-2018) databases were retrieved for literatures using the keywords of "antimicrobial, coating" in English and Chinese, respectively. RESULTS AND CONCLUSION: The currently used antimicrobial modification for orthopedic implants mainly consists of the self-antibacterial modification of the implant and the antibacterial modification on the surface of the implant. The antibacterial modification methods on the surface of the implant mainly include electrochemical modification method, magnetron sputtering method, spraying method, chemical conversion method, laser surface modification method, plasma injection method, nanosphere photolithography, sol/gel method, hydrothermal method, layer-by-layer assembly and combined treatment of various methods. Each antimicrobial modification method has its own merits and demerits.
Keywords：Prostheses and ImplantsProsthesis-Related InfectionsTissue Engineering
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 2254-2260 )