Effects of different graft materials and internal fixation methods on the intervertebral fusion time in atlantoaxial dislocation surgery
Abstract：BACKGROUND: Posterior screw-rod fixation is a popularized method in the treatment of atlantoaxial dislocation to eventually achieve intervertebral fusion. There are various graft materials and fixation methods that show different fusion time.OBJECTIVE: To analyze the effect of different graft materials and internal fixation methods on the fusion time in the posterior atlantoaxial dislocation surgery.METHODS: 286 patients with reducible atlantoaxial dislocation undergoing C1-2 posterior screw-rod fixation and obtaining successful intervertebral fusion from August 2009 to December 2015 were analyzed retrospectively. Complete pedicle screw was used for C1 screw fixation, and pedicle or laminar screws were for C2 screw fixation. The graft materials included autogenous or allogeneic grains of cancellous bone.RESULTS AND CONCLUSION: The fusion time ranged from 3 to 24 months. The fusion time did not differ significantly among fixation methods (F=2.134, P=0.120). There was significant difference in the fusion time between graft materials (F=83.611, P=0.000). Besides, there was no correlation between internal fixation methods and graft materials (F=1.036,P=0.356). These results suggest that different C1-2 posterior internal fixation methods can provide stable and reliable environment for bone fusion, and autogenous bone is more beneficial for intervertebral fusion and shortens fusion time.
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Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 1688-1694 )