Jaw bone and periodontal capillary casting in a Wistar rat model of occlusal trauma

Bi Zhen-yu; Liu Yang; Wu Bin; Xie Chun; Yang Yu-chao; Ouyang Jun

doi:10.3969/j.issn.2095-4344.2016.49.015

Abstract：BACKGROUND:Occlusal trauma, a key factor of occurrence and development of periodontal diseases, has gradual y become a hot spot of basic and clinical research. <br> OBJECTIVE:To explore the effect of occlusal trauma on jaw bone and periodontal capil aries. <br> METHODS:Forty-eight Wistar rats were enrol ed and six rats were randomly selected as control group given anesthesia only. The photo-curing material was set at the 1 mm high of right mandibular molar area in 42 rats to simulate early contact inducing occlusal trauma. Periodontal capil ary casting was conducted at 3 days, 1, 2, 3, 4, 6 and 8 weeks after modeling (6 rats per time point);the part of the jaw including teeth and periodontal tissues were isolated, and the casting specimens were observed by scanning electron microscope. <br> RESULTS AND CONCLUSION:At 3 days and 1 week after modeling, overt inflammatory reaction, slight reduction of vascular networks, and tortuous and thinner capil aries could be found, and alveolar bones had not been absorbed obviously. At 2, 3, and 4 weeks, the alveolar bones were absorbed gradual y, and the capil ary diameter and density were decreased markedly becoming more tortuous. The jaw bone absorption remained stable with increased capil aries at 6 weeks. Up to 8 weeks, abundant thinner capil aries appeared. These findings suggest that occlusal trauma wil give rise to the morphological changes of periodontal capil aries.