Posterior percutaneous pedicle screw fixation for acute thoracolumbar vertebral fractures with simple anterior spinal column injury:study protocol for a retrospective, self-controlled trial
Liang Lei
Liu Wen-de
Wu Yi-fan
Sun Xiao-hang
Ding Jun-jie
Abstract：BACKGROUND:Posterior pedicle screw fixation is commonly used for thoracolumbar fracture. However, associated disadvantages include severe trauma, extensive bleeding, long rehabilitation time, and long postoperative duration of intractable lumbar stiffness and low back pain. Percutaneous pedicle screw external fixation can reduce injury caused by screw insertion into the paraspinal muscles;particularly in acute thoracolumbar vertebral compression fracture with simple anterior spinal column injury. We hypothesized that minimal y invasive posterior percutaneous pedicle screw fixation for acute thoracolumbar vertebral fractures with simple anterior spinal column injury would exhibit good curative effects. <br> OBJECTIVE:To retrospectively analyze the curative effects of minimal y invasive posterior percutaneous pedicle screw fixation on acute thoracolumbar vertebral fractures with simple anterior spinal column injury. <br> METHODS:This retrospective, single-center, self-control ed trial was performed in PLA 153 Central Hospital, Zhengzhou, Henan Province, China. Thirty-two patients with acute thoracolumbar vertebral fracture with simple anterior spinal column injury (22 males and 10 females, average age 34.7 years, range 25-47 years) were included. Al patients underwent minimal y invasive posterior percutaneous pedicle screw internal fixation and were fol owed up for 3 months. The primary outcome measure was the Cobb angle of the injured vertebral body before, immediately after, and 3 months after internal fixation, which was used to investigate the change in the thoracolumbar spine curvature. The secondary outcome measures included:the anterior height of the injured vertebral body and radiographic findings before and immediately after internal fixation and at the last fol ow-up (to evaluate the recovery of thoracolumbar vertebral fracture), operation time, intraoperative blood loss, duration of hospitalization, and incidence of adverse events 3 months after internal fixation. The study protocol had been approved by the Ethics <br> Committee of PLA 153 Central Hospital, China and was performed in strict accordance with the Declaration of Helsinki developed by the World Medical Association. Signed informed consent regarding study protocol and treatments had been obtained from each patient. Trial registration:ClinicalTrial.gov identifier:NCT02963571;registered on November 10, 2016. <br> DISCUSSION:This study aims to validate the curative effects of minimal y invasive posterior <br> percutaneous pedicle screw fixation in acute thoracolumbar vertebral fractures with simple anterior spinal column injury, and provide objective long-term fol ow-up data for future studies.
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Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 7267-7272 )